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Men's Journal
Fortune
Sports Illustrated
New York Post
Health.com
Shape
Entrepreneur
Muscle & Fitness
Gear Patrol
MSN
Your GLP-1 Is Brilliant At Losing Weight. It Doesn't Care Which Weight.
Published trials put lean mass at 15–40% of the total weight lost on GLP-1 therapy
01
The Scale Is Telling You Half The Story
A GLP-1 doesn't target fat. It turns down appetite — and your body then decides what to burn. In the STEP-1 semaglutide trial, participants lost 15.3 kg of body weight and 6.9 kg of it was lean mass — roughly 45% of everything that came off.
That's why so many people reach goal weight and still don't like the mirror: smaller, softer, flatter. The fat left. So did the shape underneath it.
Source: Neeland et al., Diabetes Obes Metab 2024 · ADA Scientific Sessions 2025
02
Losing Muscle Is How You Regain The Fat
Muscle is your metabolic engine. Every kilogram you lose cuts your resting energy burn by about 13 calories a day — more than three times the metabolic cost of the same weight in fat.
Give up 12 lbs of muscle and you've quietly lowered your daily burn for good. That's the plateau at month five. That's the rebound after you taper off — and the regained weight tends to come back as fat, not muscle.
Source: Diabetes Obes Metab 2024 review of GLP-1 body composition data
03
Eating 900 Calories Is An Anabolic Emergency
Here's what nobody covers at the pharmacy counter. When food volume collapses, three things go wrong at the same time — and your body reads the whole situation as famine:
1Protein intake collapses → muscle has no raw material
2Cortisol climbs in a deficit → active muscle breakdown
3Zinc, boron & trace minerals go missing
4Testosterone falls → the "keep muscle" signal shuts off
Which is why the goal on a GLP-1 was never "lose weight." It's lose the fat and keep the muscle.
Xwerks Rise · GLP-1 Flash Sale
Customer-reported results
82% Of Customers Report Faster Results With XWERKS Rise
A targeted, clinically dosed formula is designed to support the full hormonal picture—not just add another underdosed ingredient to the label.
Built for the full 90 days
Track energy, training, recovery and drive.
Result trajectory
Illustrative comparison based on customer-reported experience. Individual results vary.
Rise Keeps The "Keep The Muscle" Signal Switched On
No supplement replaces protein and resistance training — those come first. But protein and lifting only pay off if your hormonal environment is telling your body that muscle is worth keeping. That signal is testosterone, and aggressive calorie restriction is one of the fastest ways to suppress it. Rise is built to defend it.
1Support natural testosterone — the retain-muscle signal
2Lower cortisol → less breakdown while eating far less
3Reduce SHBG → more free, usable testosterone
4Replace minerals low food volume can't deliver
On a GLP-1, fat loss is the easy part. Muscle retention is the whole game.
5 Actives. Every Dose On The Label.
No proprietary blends. No filler. Clinically studied doses — chosen for exactly the problem a deep calorie deficit creates.
Tongkat Ali
400 mgA best-in-class dose of longjack root, studied for supporting free testosterone and lowering cortisol — the catabolic hormone that climbs in a deep deficit and pulls muscle tissue apart.
Shilajit
250 mgHimalayan resin rich in fulvic acid and 84+ trace minerals. Mineral repletion for a body that simply isn't eating enough food volume to get them, plus support for energy and strength retention.
Zinc
15 mg136% of your daily value. Essential for testosterone synthesis, IGF-1 and muscle repair — and one of the first minerals to fall short when portion sizes shrink.
Boron
6 mgLowers SHBG by roughly 9% within hours, so more of your own testosterone stays free and usable. Also improves vitamin D and magnesium absorption.
BioPerine®
10 mgPatented black-pepper extract that raises absorption of everything above by up to 200% — which matters more than usual when your digestion is slower on a GLP-1.
Built for the deficit
Two capsules a day. Caffeine-free, so it won't touch your sleep. No cycling and no post-cycle protocol, because Rise supports your own production rather than replacing it.
What The Next 90 Days Look Like
Same medication. Same appetite suppression. A very different body composition at the end of it.
WEEK 1
Minerals Back In
Zinc, boron and shilajit's trace minerals refill what a 900-calorie day can't supply.
Energy Off The Floor
Most users say the GLP-1 flatness and the afternoon crash are the first things to ease.
Cortisol Comes Down
Tongkat Ali begins blunting the stress-hormone spike that a hard deficit creates.
★★★★★
"Three weeks after my dose increase I was wiped out and my lifts were falling off. Two weeks on Rise and my sessions came back — same medication, same food."
Kevin W. — age 42
WEEK 4
Anabolic Signal Restored
Free testosterone support means your body stops treating muscle as a convenient fuel source.
Strength Stops Sliding
The number on the bar holds steady — the clearest day-to-day sign lean mass is staying put.
Recovery Speeds Up
Zinc and shilajit support the tissue repair that low-calorie eating slows right down.
★★★★★
"My first round on a GLP-1 I lost my legs. Round two with Rise and real protein, my squat is up 20 lbs while I'm down 19."
Marcus D. — age 53
WEEK 12
Fat Down, Shape Intact
The scale still moves — but the mirror shows definition instead of deflation.
Metabolism Defended
Holding onto muscle protects the resting burn that makes maintenance realistic later.
The Handoff
When you taper off the medication, you come off with the engine that keeps the weight off.
★★★★★
"Down 41 lbs total and my last scan came back with lean mass basically unchanged. My doctor asked what I was doing differently."
Ronald K. — age 38
"Same Shot. Same Deficit. My Muscle Stayed."
Rise is the piece most GLP-1 protocols leave out.
Protect Your Muscle — Try RiseEven The Drug Companies Admit This Is The Next Problem To Solve
The race to make GLP-1 weight loss "higher quality" has already started
GLP-1 prescriptions in the United States have climbed 587% in five years, and the conversation among clinicians has already moved past how much weight comes off to what kind of weight comes off.
At the American Diabetes Association's 2025 Scientific Sessions, researchers presented the BELIEVE trial: pairing semaglutide with a muscle-sparing agent pushed the share of weight lost as fat from 71.8% up to 92.8%. The message from the podium was blunt — it is possible to lose the fat and keep, or even add, lean mass.
That drug is years and thousands of dollars away from your medicine cabinet. What's available today is what every endocrinologist already recommends: adequate protein, resistance training two to three times a week, and support for the hormonal environment that decides whether your body holds onto muscle.
Rise covers that third piece for about $1.47 a day.
Sources: ADA 85th Scientific Sessions press release, June 2025 · FAIR Health white paper on GLP-1 utilisation
Protein And Lifting Alone Aren't Enough — And It's Not Your Fault
Every credible muscle-preservation protocol rests on three legs. Miss one and the other two are carrying a load they were never meant to hold.
Protein
Supplies the raw material — 1.2 to 1.6 g per kg of bodyweight.
Appetite suppression makes 140 g of protein a day feel impossible.
Resistance Training
Sends the mechanical 'keep this tissue' message to the muscle.
Low-calorie fatigue quietly kills training volume and intensity.
Hormonal Signal
Decides whether the protein you eat gets built or burned.
Almost nobody addresses it. This is the gap Rise was built for.
You can force down the protein and drag yourself to the gym. But if testosterone is suppressed and cortisol is elevated, your own physiology is working against the effort.
Rise addresses the leg nobody talks about.
Limited Muscle-Preservation Sale
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60 Capsules · 30-Day Supply · 2 Capsules Daily
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Questions? Answered.
Can I take Rise alongside my GLP-1 medication?
Rise is a caffeine-free dietary supplement made from natural ingredients at clinically studied doses — it is not a hormone and not a drug, and it does not change how your medication works. That said, anyone on a prescription medication should confirm with their prescribing physician before adding any supplement. Bring the label to your next appointment.
Will this interfere with the appetite suppression I'm paying for?
No. Rise contains no stimulants and no appetite-affecting compounds. Your medication does its job on appetite; Rise supports the hormonal environment that determines whether the weight coming off is fat or muscle.
How much muscle do people actually lose on a GLP-1?
It varies by drug, dose and lifestyle. Published trials put lean mass at roughly 15–40% of total weight lost, and the STEP-1 semaglutide trial came in near 45%. People who add adequate protein and resistance training consistently retain considerably more.
Do I still need to lift and eat protein?
Yes, and no supplement changes that. Aim for 1.2 to 1.6 grams of protein per kilogram of bodyweight and two to three resistance sessions a week. Rise is designed to make that work count — not to replace it.
How fast will I feel it?
Most users report better energy, sleep and mood within the first one to two weeks. Strength and body-composition changes typically show up around weeks three to four, with peak benefits after two to three months of consistent daily use.
What exactly is in Rise?
Tongkat Ali 400 mg, Shilajit 250 mg, Zinc 15 mg (136% DV), Boron 6 mg, and BioPerine® 10 mg for absorption. Two capsules a day, 60 capsules per bottle. No proprietary blends, no fillers, no dyes, manufactured in GMP-certified US facilities.
Is it safe? Any side effects?
Most users report none. Take with food to maximise absorption and comfort. If you take prescription medications — including GLP-1 medications — or have a medical condition, consult your physician before starting.
What if it doesn't work for me?
You're covered by a 30-day, no-questions money-back guarantee. If you don't feel the difference, reach out within 30 days for a full refund.