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For Men on GLP-1 Medications
Your GLP-1 Is
Burning Muscle.
Not Just Fat.
Up to 40% of the weight you lose on Ozempic, Wegovy, Mounjaro, or Zepbound comes from lean mass — including muscle. Your testosterone is tanking in the process. Rise is formulated to fight back: 4 clinically-dosed ingredients that naturally optimize testosterone production, protect lean mass, and keep your hormonal system from collapsing while GLP-1 strips the fat.
40%
Weight Loss = Muscle
↓ T
Testosterone Drops
Rise
Fights Both
GMP Certified
No Synthetic Hormones
Made in USA
Third-Party Tested
85+ Reviews
As Featured In
FortuneMen's JournalSports IllustratedGarage Gym ReviewsHealth.comMuscle & FitnessShapeEntrepreneur
FortuneMen's JournalSports IllustratedGarage Gym ReviewsHealth.comMuscle & FitnessShapeEntrepreneur
Fortune
"For individuals seeking to enhance muscle growth through a testosterone booster, Xwerks Rise is a great place to start."
Men's Journal
"XWERKS products stand out for high-quality sourcing and clean, research-backed formulas."
Garage Gym Reviews
"Rise uses clinically-studied ingredients at proper doses — not the under-dosed proprietary blends you see everywhere."
10+
Publications
85+
Reviews
30K+
Customers
The GLP-1 Blind Spot
Your Medication Is Working. Your Muscles Are Paying the Price.
GLP-1 drugs like semaglutide and tirzepatide are phenomenal at burning fat. But the research is clear: up to 40% of the weight you lose is lean mass — including skeletal muscle. That's not a minor side effect. That's your metabolism, your strength, and your functional capacity disappearing along with the fat.
It gets worse. Rapid weight loss drives testosterone into the ground. Lower T means less muscle protein synthesis, more cortisol, more fatigue, and a body that's getting lighter on the scale but weaker in every way that matters.
Rise attacks both problems simultaneously. Tongkat Ali directly stimulates testosterone production. Shilajit fuels it at the cellular level. Boron frees bound testosterone so your body can actually use it. And zinc fills the nutritional gap that GLP-1's appetite suppression creates. Your medication handles the fat. Rise handles everything else.
~40%
Lean Mass Lost on GLP-1
↓ T
Testosterone Decline
↓ BMR
Slower Metabolism
Rise
Natural T Optimization
4 Angles of Defense
How Rise Protects GLP-1 Users
Boosts T Production
Tongkat Ali (400mg) directly stimulates gonadotropin signaling — the hormonal pathway GLP-1 weight loss is suppressing. More T means more muscle protein synthesis when you need it most.
Frees Bound T
Boron (6mg) reduces SHBG by ~9% within hours. That means more of the testosterone your body makes is actually bioavailable — not locked up and useless.
Fills Nutrient Gaps
GLP-1 crushes appetite — and with it, your intake of critical minerals. Zinc (15mg, 136% DV) replenishes the deficit that's accelerating your hormonal decline.
Cellular Energy
Shilajit (250mg) delivers 84+ minerals and fulvic acid directly to your cells. Fights the fatigue and brain fog that GLP-1 users report during rapid weight loss phases.
Personalized Data
How Much Muscle Is Your GLP-1 Costing You?
40 lbs
10 lbs120 lbs
Where Your Weight Loss Came From
*Projection based on published research: Tongkat Ali has been shown to improve lean body mass and body composition (Henkel et al., 2014). Shilajit supports testosterone in men (Pandit et al., 2016). Testosterone optimization is associated with reduced lean mass loss during caloric deficit. Individual results will vary.
Estimated Muscle Lost
16 lbs
That's the equivalent of losing all the muscle in both your arms. Gone. And your metabolism just dropped with it.
Metabolic Impact
-96 cal/day
Every pound of muscle burns ~6 calories at rest. You've permanently slowed your metabolism by this amount — making future weight regain more likely.
Potential Muscle Preserved With Rise*
~5 lbs
Optimized testosterone supports muscle protein synthesis during caloric deficit. That's the difference between looking skinny-fat and looking lean and strong.
The math is simple: GLP-1 handles the fat. Rise handles the muscle. Without testosterone optimization, you're losing both.
Transparent Label. Clinical Doses.
What's In Rise
400mg
Tongkat Ali
Stimulates gonadotropin production, reduces SHBG, supports lean mass preservation. The highest clinical dose — not the 100–200mg others use.
250mg
Shilajit
84+ minerals and fulvic acid. Supports testosterone at the cellular level and combats the fatigue GLP-1 users experience during rapid weight loss.
15mg
Zinc
136% daily value. Critical for testosterone metabolism — and the first mineral to deplete when GLP-1 suppresses your appetite and food intake.
6mg
Boron
Reduces SHBG ~9% within hours, increasing free testosterone. Also blocks estrogen conversion — key when body composition is shifting rapidly.
+ BioPerine (10mg) — enhances absorption of all ingredients by up to 200%.
Why Not Just TRT?
Rise vs. TRT for GLP-1 Users
| XWERKS Rise | TRT | |
|---|---|---|
| GLP-1 Compatible | ✓ No interactions | ⚠ Requires monitoring |
| Approach | ✓ Natural support | ✕ Synthetic replacement |
| Doctor Required | ✓ No | ✕ Yes — ongoing |
| Shuts Down Natural T | ✓ No — supports it | ✕ Yes — permanently |
| Cost | ✓ $49/mo | ✕ $250+/mo |
| Side Effects | ✓ Minimal | ✕ Erythrocytosis, sleep apnea, CV risk |
| Can Stop Anytime | ✓ Yes | ✕ Difficult — dependency |
| Already on GLP-1 Meds | ✓ Simple addition | ✕ Complex protocol stacking |
85+ Verified Reviews
What Men Are Saying
★★★★★
"Energy Came Back"
I started Rise two months into my Wegovy treatment. The fatigue was brutal — couldn't get through workouts. Within two weeks of adding Rise, my energy stabilized and my lifts stopped declining. Game changer for anyone on GLP-1.
Verified Buyer
★★★★★
"Kept My Muscle"
Lost 35 lbs on semaglutide but I could see the muscle going too. Added Rise and Ashwa together. Strength came back, body composition improved dramatically. I look lean now — not just skinny.
Verified Buyer
★★★★★
"Should Be Standard Protocol"
My doctor has me on tirzepatide and I was losing strength fast. Rise doesn't interfere with anything — just fills in what the medication takes out. Better sleep, better mood, better gym sessions.
Verified Buyer
GLP-1 + Rise
Frequently Asked
Rise contains natural ingredients (Tongkat Ali, Shilajit, Zinc, Boron, BioPerine) with no known drug interactions with GLP-1 receptor agonists. That said, always consult your prescribing physician before adding any supplement to your regimen. Rise supports your body's natural hormone production — it doesn't introduce synthetic hormones.
GLP-1 drugs create a significant caloric deficit through appetite suppression. During rapid weight loss, 25–40% of the weight lost comes from lean mass including muscle (SURMOUNT-1 trial, STEP trials). This is compounded by reduced protein intake from suppressed appetite and potential hormonal disruption from rapid body composition changes. The research is published across multiple journals including the NEJM and Nature Reviews Endocrinology.
Rise works by optimizing testosterone — the primary anabolic hormone responsible for muscle protein synthesis. Tongkat Ali has been shown in clinical studies to improve testosterone levels by 15–37% and support lean body mass. When your body has adequate testosterone, it prioritizes fat loss over muscle loss during caloric deficit. Rise also replenishes zinc, which is one of the first minerals depleted when appetite is suppressed.
If you're on TRT under medical supervision, your testosterone levels are already being managed exogenously. Rise is designed for men who want to optimize testosterone naturally without TRT — particularly those who want a simpler approach alongside their GLP-1 medication without adding another prescription to the stack.
Ideally, as early as possible. Muscle loss begins in the first weeks of GLP-1 treatment and compounds over time. Starting Rise early gives your body the hormonal support it needs to preserve lean mass from day one. But it's never too late — even months into treatment, optimizing testosterone can help rebuild what's been lost.
Yes — Xwerks recommends combining Rise with Ashwa (KSM-66 ashwagandha gummies) for cortisol control and Grow (whey protein isolate) to ensure adequate protein intake. GLP-1 users particularly benefit from the Grow + Rise combination: Grow provides 25g of pure protein per scoop to combat the reduced food intake, while Rise optimizes the hormonal environment to actually use that protein for muscle maintenance.
30 DAY
MONEY
BACK
MONEY
BACK
Risk-Free. Like Your Medication Should Be.
Try Rise for 30 days alongside your GLP-1 treatment. If you don't feel the difference — more energy, better gym sessions, improved body composition — full refund. No questions.
Try Rise Risk-FreeYour GLP-1 Handles Fat.
Rise Handles Everything Else.
Protect your muscle. Optimize your testosterone. Don't let your medication's biggest blind spot undo the work you're putting in.
$49
30-day supply · $1.63/day · Free shipping over $75
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